Generated on: 06-09-23 01:34:28

Studies Unique Samples per Visibility Status Public Samples per Data Type Users Jobs
public: 698
private: 155
sandbox: 2,330
submitted to EBI: 736
public: 373,866
private: 111,214
sandbox: 473,484
submitted to EBI: 274,745
submitted to EBI (prep): 324,537
16S: 342,835
18S: 8,896
ITS: 14,156
Metagenomic: 60,670
Full Length Operon: 803
Metatranscriptomic: 11,764
Metabolomic: 407
Genome Isolate: 1,131
11,822 666,147

Check out this random public study from the database!

Determination of how APE1 protects the digestive tract from DNA damage initiated by commensal bacteria

Our project focuses on apurinic/apyrimidinic endonuclease (APE1), a multifunctional protein that regulates stress induced by carcinogenic infections. We developed a hypomorphic (HM) mouse that has facilitated studies of APE1 function throughout the body. The major finding is that the digestive tract is particularly susceptible to DNA damage when APE1 is compromised. The broad objective of this grant is to define how APE1 protects the digestive tract from DNA damage initiated by comensal bacteria

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