Generated on: 09-06-24 01:28:41

Studies Unique Samples per Visibility Status Public Samples per Data Type Users Jobs
public: 803
private: 171
sandbox: 2,611
submitted to EBI: 856
public: 397,513
private: 116,094
sandbox: 564,550
submitted to EBI: 317,331
submitted to EBI (prep): 371,005
16S: 365,931
18S: 12,113
ITS: 14,649
Metagenomic: 65,704
Full Length Operon: 803
Metatranscriptomic: 11,797
Metabolomic: 407
Genome Isolate: 1,131
13,431 793,902

Check out this random public study from the database!

The Gastrointestinal and Microbiome Impact of a Resistant Starch Blend: A Randomized Clinical Trial Using Smart Caps

The gastrointestinal (GI) impact of resistant starch consumption depends on microbiomes, adherence, and various types and amounts of resistant starch. A randomized clinical trial with smart cap monitoring was used to evaluate the GI impact of a novel resistant starch blend (RSB) at varying doses. The study design randomized participants to a potato starch as a control or one of three arms ramping doses from 10 to 30 g /day over 6 weeks of RSB, a proprietary mixture of a different potato starch, green banana flour and apple fiber powder. The blend contained at least 50% resistant starch. Total short-chain fatty acids (SCFA) increased with increasing doses of the RSB. GI symptoms improved in all groups, and the increasing doses of RSB led to a decrease in the diarrhea score. Using an estimate of total consumption of RSB based on smart cap recordings of container openings and protocol-specified doses, we showed that a reduction in the sleep disturbance score was associated with higher RSB dose. The microbiome evaluation demonstrated that among the 16S sequences most associated with the consumption of the novel blend RSB, two belong to taxa of notable interest to human health: Faecalibacterium and Akkermansia.

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